Workplaces told to plan for absences of up to 25%, Marketing & PR Services in Reading, Berkshire
Public sector leaders have been asked to prepare for "worst-case scenarios" of 10%, 20%, and 25% absence rates, the Cabinet Office said.
The UK has seen record numbers of daily cases over the festive period.
Transport, the NHS, and schools have already seen the effect of absences.
Rising case numbers have led to large numbers self-isolating and being unable to go to work. This has particularly affected industries where staffs are unable to work from home.